I can't wake up in the morning and then fall back to sleep for half and hour, and i want my coffee now when i get up (it's brewed on a timer and sitting there just waiting for me). In studies, coffee reduced the body’s absorption of thyroid medications by about 30%. Pin On Thyroid Health No cream, no milk, etc. Synthroid and coffee in the morning . You are being given correct advice. Another culprit is t4 taken with with coffee. There is consensus that levothyroxine should why take synthroid in the morning taken in the morning on an empty stomach. This is why you feel a sudden. Research suggests that taking levothyroxine at night may improve absorption of the drug. Coffee stimulates the adrenals to secrete cortisol. They just do not consider coffee as food , but rather they think it’s a beverage like water; 8) you take your synthroid or levothyroxine with coffee. Dairy can interfere with the absorption of synthroid, making it not work as it is intended to...